The impenetrable fog of politics

Driving over the hills to Clare, the fog lay impenetrable as that surrounding the future of so many in this Covid time. We have been upped to tier 2 with its greater restrictions; other areas fare worse, being jacked up to tier 3, full lockdown in all but name. My own instinct is still that, for freedom's and the economy's sakes, the tiers should have been arranged by personal risk rather than blanket bans to everyone by area. The young and healthy (say all under 50 or 55 years) should be given total freedom for work, education, and visiting each other, with isolation only if they are ill with the dreaded CV. All others should isolate according to age and risk factors. I have been sent an official notice that I am extremely vulnerable, so it makes sense for me to lock myself away and see no one from outside; but healthy people in their 60's or 70's could take minor risks by going to shops, or meeting people at a distance. But sense does not rule this country. If Doom and Gloom (Whitty Vallance) were advising to reduce overall deaths in the population, they would no doubt make drinking and smoking verboten. 

To emphasise the gloom of the fog and the lockdowns, they were preparing a horse drawn hearse in Clare park ready for a funeral this afternoon. It looks as though the Clare Godfather has died. We were all told to keep clear of the area and keep dogs on a short lead. 

The safety and efficacy of the Oxford vaccine is being doubted because the effective dose appears to have been discovered accidentally. I would like to reassure my few readers that serendipity plays a major role in chemistry and drug discovery. Most people know that Viagra was a new Pfizer drug  expected to work in the treatment of angina but, instead of relieving anginal pain, it induced unwanted penile erections in some patients. I was with Pfizer when they held the biggest party I’ve been to with the launch of Viagra. Librium was placed on the shelf but was found again by accident literally during a, laboratory cleanup, and submitted for clinical trials before they threw it away. Aniline dyes, LSD, penicillin, Warfarin, digoxin, the anti-depressant Tofranil, the anti-psychotic Largactil were all serendipitous discoveries. Indeed, it is thought that 6% of useful drugs are found by luck, so my guess is that the Oxford vaccine will do very well..

We still hope to host our Christmas day family celebration. It looks as though three families will be allowed to gather, so that's us, MA and Sam and their children, and Eds and Andre plus Andre's sister. She comes over from Brazil at the weekend and will be staying for a couple of nights. Ann has ordered the traditional lucky dip presents in anticipation that all will go ahead normally.